Development, Cross-Cultural Adaptation, and Psychometric Characteristics of the Persian Progressive Aphasia Language Scale in Patients With Primary Progressive Aphasia: A Pilot Study

Basic and Clinical Neuroscience

ARTICLE

Jafari, Salime¹  Modarresszadeh, Amin¹  Khatoonabadi, Ahmad Reza¹  Hodges, John²  Nakhostin Ansari, Noureddin³  Leyton, Cristian⁴  Noroozian, Maryam⁵ 

[1] Department of Speech Therapy, School of Rehabilitation, Tehran University of Medical Sciences;Brain & Mind Centre, The University of Sydney;Department of Physiotherapy, School of Rehabilitation, Tehran University of Medical Sciences;Faculty of Health Sciences, The University of Sydney;Memory and Behavioral Neurology Division, Roozbeh Hospital, Tehran University of Medical Sciences

关键词: Aphasia;    Neurodegenerative disorders;    Primary progressive aphasia;    Language test;   

DOI  :  10.29252/nirp.bcn.9.1.35

来源: Iran University of Medical Sciences

【 摘 要 】

Introduction: Primary Progressive Aphasia (PPA) is a neurological condition characterized by progressive dissolution of language capabilities. The Progressive Aphasia Language Scale (PALS) is an easy-to-apply bedside clinical scale capable of capturing and grading the key language features essential for the classification of PPA. The objective of the present study was to develop and validate the Persian version of the PALS (PALS-P) as a clinical language assessment test. Methods: In this cross-sectional study, PALS was translated and adapted into Persian according to the international guidelines. A total of 30 subjects (10 subjects with PPA and 20 control subjects without dementia) were recruited to evaluate the intra-rater reliability and discriminant validity of PALS-P. Results: The intra-rater reliability of the PALS-P within a 14-day interval was excellent for each subtest (ICC agreement range=0.81-1.0). PALS-P results were statistically significant among groups, suggesting its discriminative validity. Conclusion: This preliminary study indicates that PALS-P was successfully developed and translated. It seems to be a valid and reliable screening tool to assess language skills in Persianspeaking subjects with progressive aphasia.

【 授权许可】

Unknown