The Effect of Repetitive Transcranial Magnetic Stimulation on Postural Stability After Acute Stroke: A Clinical Trial

Basic and Clinical Neuroscience

ARTICLE

Forogh, Bijan¹  Ahadi, Tannaz¹  Nazari, Maryam¹  Sajadi, Simin¹  Abdul Latif, Lydia²  Akhavan Hejazi, Seyed Majid²  Raissi, Gholamreza¹ 

[1] Neuromusculoskeletal Research Center, Firoozgar Hospital;Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya

关键词: Stroke;    Transcranial magnetic stimulation;    Stroke rehabilitation;    Postural balance;    Proprioception;   

DOI  :  10.18869/nirp.bcn.8.5.405

来源: Iran University of Medical Sciences

【 摘 要 】

Introduction: Balance impairment is a common problem and a major cause of motor disability after stroke. Therefore, this study aimed to investigate whether low-frequency repetitive Transcranial Magnetic Stimulation (rTMS) improves the postural balance problems in stroke patients. Methods: This randomized double blind clinical trial with 12 weeks follow-up was conducted on stroke patients. Treatment was carried with 1 Hz rTMS in contralateral brain hemisphere over the primary motor area for 20 minutes (1200 pulses) for 5 consecutive days. Static postural stability, Medical Research Council (MRC), Berg Balance Scale (BBS), and Fugl-Meyer assessments were evaluated immediately, 3 weeks and 12 weeks after intervention. Results: A total of 26 patients were enrolled (age range=53 to 79 years; 61.5% were male) in this study. Administering rTMS produced a significant recovery based on BBS (df=86, 7; F=7.4; P=0.01), Fugl-Meyer Scale (df=86, 7; F=8.7; P<0.001), MRC score (df=87, 7; F=2.9; P=0.01), and static postural stability (df=87, 7; F=9.8; P<0.001) during the 12 weeks follow-up. Conclusion: According to the findings, rTMS as an adjuvant therapy may improve the static postural stability, falling risk, coordination, motor recovery, and muscle strength in patients with stroke.

【 授权许可】

Unknown