BK Nephropathy in Renal Transplant Patients with Epididymo-Orchitis

Journal of Comprehensive Pediatrics

ARTICLE

Moghtaderi, Mastaneh¹  Abedzadeh, Aliasghar²  Vasei, Mahmmad³ 

[1] Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences;School of Medicine, Tehran University of Medical Sciences;Pediatrics Centre of Excellence, Department of Pediatric Neurology, Children's Medical Centre Hospital, Tehran University of Medical Sciences

关键词: Renal Transplant;    BK Virus;    BK Nephropathy;   

DOI  :  10.5812/compreped.56004

来源: Kowsarmedical

【 摘 要 】

The patient was a 10-year-old male that was transplanted six months prior to this study. He was admitted because of epididymo-orchitis, pyuria, glucosuria, and rising blood urea nitrogen (BUN) and creatinine (Cr). BK viruria copy number was 50,000,000. In renal biopsy examination, acute cellular rejection was reported. The diagnosis was BK virus epididymo orchitis with BK allograft nephropathy. His treatment was started by discontinuation of tacrolimus and mycophenolate and starting of leflunomide and low dose prednisolone. After improvement of renal dysfunction and BK load, the treatment regimen was changed to cyclosporine and sirolimus. Renal function after the one-year follow up did not change and remained in a good condition.

【 授权许可】

Unknown