Mediterranean Journal of Rheumatology September 2018 Highlights

Mediterranean Journal of Rheumatology

ARTICLE

Dimitrios P. Bogdanos¹ 

[1] Department of Rheumatology and Clinical Immunology, University General Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly

DOI  :  10.31138/mjr.29.3.118

学科分类：社会科学、人文和艺术（综合）

来源: PCO Convin S.A.

【 摘 要 】

In this issue of the Journal, original papers, reviews, case studies and research protocols related to the broad spectrum of rheumatic diseases are published. All of them are of interest, discuss novel issues and significantly contribute to the ongoing translational research and clinical practice in the field of rheumatology. In their original article, Sakkas and collaborators report the multiparametric autoantibody profile of their patients with systemic sclerosis (SSc) and morphea.1 What is new in this single-centre study is the appreciation that patients with morphea have entirely distinct autoantibody profile from patients with SSc. This study, which is the most comprehensive analysis of autoantibody profiling of 13 systemic sclerosis related autoantibodies in Greek patients with systemic sclerosis, points towards the need to include anti-RNA pol III antibodies in the routine testing of patients with clinical suspicion of systemic sclerosis as this increases the diagnostic sensitivity of autoantibody detection. It suggests that if anti-CEN, anti-Topo I and anti-RNA pol III antibodies are negative but the clinical suspicion remains high, physicians may need to assess for the remaining autoantibody specificities by specialized laboratories.

【 授权许可】

CC BY-NC