Clinical Characteristics of Chronic Cough in Korea

Tuberculosis and Respiratory Diseases

article

Tai Joon An¹  Jin Woo Kim²  Eun Young Choi³  Seung Hun Jang⁴  Hwa Young Lee⁵  Hye Seon Kang⁶  Hyeon-Kyoung Koo⁷  Jong Min Lee⁵  Sung-Kyung Kim⁸  Jong-Wook Shin⁹  So Young Park^1,10  Chin Kook Rhee⁵  Ji-Yong Moon^1,11  Yee Hyung Kim^1,12  Hyun Lee^1,13  Yong Hyun Kim⁶  Je Hyeong Kim^1,14  Sang Haak Lee^1,15  Deog Kyeom Kim^1,16  Kwang Ha Yoo^1,17  Dong-Gyu Kim^1,18  Ki-Suck Jung⁴  Hui Jung Kim^1,19  Hyoung Kyu Yoon¹ 

[1] Division of Pulmonary, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea;Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea;Division of Pulmonary and Allergy, Department of Internal Medicine, Regional Respiratory Center, Yeungnam University Hospital;Division of Pulmonary, Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine;Division of Pulmonary, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea;Division of Pulmonary, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine;Division of Pulmonology, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea;Division of Pulmonary, Department of Internal Medicine, Chung-Ang University College of Medicine;Division of Pulmonary and Critical Care Medicine, Chungnam University Medical Center;Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine;Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong;Department of Internal Medicine, Hanyang University College of Medicine;Division of Pulmonary, Department of Internal Medicine, Korea University Ansan Hospital;Division of Pulmonary, Department of Internal Medicine, St. Paul's Hospital, College of Medicine, The Catholic University of Korea;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine;Division of Pulmonary, Department of Internal Medicine, Konkuk University School of Medicine;Division of Pulmonary, Hallym University Kangnam Sacred Heart Hospital;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine

关键词: Cough;    Cohort Studies;    Epidemiology;    Guideline;    Diagnosis;    Disease Management;   

DOI  :  10.4046/trd.2019.0018

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Background Chronic cough is defined as a cough lasting more than 8 weeks and socio-economic burden of chronic cough is enormous. The characteristics of chronic cough in Korea are not well understood. The Korean Academy of Tuberculosis and Respiratory Diseases (KATRD) published guidelines on cough management in 2014. The current study evaluated the clinical characteristics of chronic cough in Korea and the efficacy of the KATRD guidelines. Methods This was a multi-center, retrospective observational study conducted in Korea. The participants were over 18 years of age. They had coughs lasting more than 8 weeks. Subjects with current pulmonary diseases, smokers, ex-smokers with more than 10 pack-years or who quit within the past 1 year, pregnant women, and users of cough-inducing medications were excluded. Evaluation and management of cough followed the KATRD cough-management guidelines. Results Participants with chronic cough in Korea showed age in the late forties and cough duration of more than 1 year. Upper airway cough syndrome was the most common cause of cough, followed by cough-variant asthma (CVA). Gastro-esophageal reflux diseases and eosinophilic bronchitis were less frequently observed. Following the KATRD cough-management guidelines, 91.2% of the subjects improved after 4 weeks of treatment. Responders were younger, had a longer duration of cough, and an initial impression of CVA. In univariate and multivariate analyses, an initial impression of CVA was the only factor related to better treatment response. Conclusion The causes of chronic cough in Korea differed from those reported in other countries. The current Korean guidelines proved efficient for treating Korean patients with chronic cough.

【 授权许可】

CC BY-NC