Determinants of Nicotine Dependence in Chronic Obstructive Pulmonary Disease

Tuberculosis and Respiratory Diseases

article

Yun Su Sim¹  Jin Hwa Lee²  Ki Uk Kim³  Seung Won Ra⁴  Hye Yun Park⁵  Chang-Hoon Lee⁶  Deog Kyeom Kim⁷  Kyeong-Cheol Shin⁸  Sang Haak Lee⁹  Hun Gyu Hwang^1,10  Joong Hyun Ahn^1,11  Yong Bum Park^1,12  Yu-Il Kim^1,13  Kwang Ha Yoo^1,14  Ina Jeong^1,15  Yeon-Mok Oh^1,16  Sang-Do Lee^1,16 

[1] Division of Pulmonary, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital;Division of Pulmonary and Critical Care Medicine, Department of Medicine, Ewha Womans University School of Medicine;Department of Internal Medicine, Pusan National University School of Medicine;Division of Pulmonary Medicine, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine;Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine;Regional Center for Respiratory Disease, Yeungnam University Medical Center, Yeungnam University College of Medicine;Department of Internal Medicine, St. Paul's Hospital, College of Medicine, The Catholic University of Korea;Respiratory Division, Department of Internal Medicine, Soonchunhyang University Gumi Hospital, Soonchunhyang University College of Medicine;Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon;Department of Pulmonary and Critical Care Medicine, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine;Department of Internal Medicine, Chonnam National University Hospital;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Medical Center;Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine

关键词: Nicotine Dependence;    Pulmonary Disease;    Chronic Obstructive;    Smoking Cessation;   

DOI  :  10.4046/trd.2017.80.3.277

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Background Smoking cessation is the most powerful intervention to modify progress of chronic obstructive pulmonary disease (COPD), and nicotine dependence is one of the most important determinants of success or failure in smoking cessation. We evaluated nicotine dependence status and investigated factors associated with moderate to high nicotine dependence in patients with COPD. Methods We included 53 current smokers with COPD in the Korean Obstructive Lung Disease II cohort enrolled between January 2014 and March 2016. Nicotine dependence was measured by using Fagerstrom test for nicotine dependence (FTND). Cognitive function was assessed by Korean version of Montreal Cognitive Assessment. Results The median FTND score was 3, and 32 patients (60%) had moderate to high nicotine dependence. The median smoking amount was 44 pack-years, which was not related to nicotine dependence. Multiple logistic regression analysis revealed that high education status (odds ratio, 1.286; 95% confidence interval, 1.036-1.596; p=0.023), age <70 (odds ratio, 6.407; 95% confidence interval, 1.376-29.830; p=0.018), and mild to moderate airflow obstruction (odds ratio, 6.969; 95% confidence interval, 1.388-34.998; p=0.018) were related to moderate to high nicotine dependence. Conclusion Nicotine dependence does not correlate with smoking amount, but with education level, age, and severity of airflow obstruction. Physicians should provide different strategies of smoking cessation intervention for current smokers with COPD according to their education levels, age, and severity of airflow obstruction.

【 授权许可】

CC BY-NC