Unplanned Extubation in Patients with Mechanical Ventilation: Experience in the Medical Intensive Care Unit of a Single Tertiary Hospital

Tuberculosis and Respiratory Diseases

article

Tae Won Lee¹  Jeong Woo Hong¹  Jung-Wan Yoo¹  Sunmi Ju¹  Seung Hun Lee¹  Seung Jun Lee¹  Yu Ji Cho¹  Yi Yeong Jeong¹  Jong Deog Lee¹  Ho Cheol Kim¹ 

[1] Department of Internal Medicine, Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine

关键词: Airway Extubation;    Respiration;    Artificial;    Intensive Care Units;   

DOI  :  10.4046/trd.2015.78.4.336

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Background Potentially harmful unplanned extubation (UE) may occur in patients on mechanical ventilation (MV) in an intensive care unit (ICU) setting. This study aimed to evaluate the clinical characteristics of UE and its impact on clinical outcomes in patients with MV in a medical ICU (MICU). Methods We retrospectively evaluated MICU data prospectively collected between December 2011 and May 2014. Results A total of 468 patients were admitted to the MICU, of whom 450 were on MV. Of the patients on MV, 30 (6.7%) experienced UE; 13 (43.3%) required reintubation after UE, whereas 17 (56.7%) did not require reintubation. Patients who required reintubation had a significantly longer MV duration and ICU stay than did those not requiring reintubation (19.4±15.1 days vs. 5.9±5.9 days days and 18.1±14.2 days vs. 7.1±6.5 days, respectively; p<0.05). In addition, mortality rate was significantly higher among patients requiring reintubation than among those not requiring reintubation (54.5% vs. 5.9%; p=0.007). These two groups of patients exhibited no significant differences, within 2 hours after UE, in the fraction of inspired oxygen, blood pressure, heart rate, respiratory rate, and pH. Conclusion Although reintubation may not always be required in patients with UE, it is associated with a poor outcome after UE.

【 授权许可】

CC BY-NC