A Case of Venlafaxine-Induced Interstitial Lung Disease

Tuberculosis and Respiratory Diseases

article

Serim Oh¹  Seung-Ick Cha¹  Hyera Kim¹  Minjung Kim¹  Sun Ha Choi¹  Hyewon Seo¹  Tae-In Park² 

[1] Department of Internal Medicine, Kyungpook National University School of Medicine;Department of Pathology, Kyungpook National University School of Medicine

关键词: Hypersensitivity;    Pneumonia;    Lung Disease;    Interstitial;    Venlafaxine;   

DOI  :  10.4046/trd.2014.77.2.81

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

A patient treated with venlafaxine for major depression developed an interstitial lung disease (ILD) with the characteristic clinical, radiological and pathological features of chronic hypersensitivity pneumonitis. A high resolution computed tomography scan demonstrated ground glass opacity, mosaic perfusion with air-trapping and traction bronchiectasis in both lungs. The pathological findings were consistent with a nonspecific interstitial pneumonia pattern. Clinical and radiological improvements were noted after the discontinuation of venlafaxine and the administration of a corticosteroid. This report provides further evidence that the anti-depressant venlafaxine can cause ILD.

【 授权许可】

CC BY-NC