A Case of Invasive Pulmonary Aspergillosis with Direct Invasion of the Mediastinum and the Left Atrium in an Immunocompetent Patient

Tuberculosis and Respiratory Diseases

article

Kyu-Hyun Han¹  Jung-Hyun Kim¹  Sun Young Shin¹  Hye Yun Jeong¹  Ji Min Chu¹  Hak Su Kim¹  Daejin Kim¹  Minjung Shim¹  Sang-Ho Cho²  Eun Kyung Kim¹ 

[1] Department of Internal Medicine, CHA Bundang Medical Center, CHA University;Department of Pathology, CHA Bundang Medical Center, CHA University

关键词: Invasive Pulmonary Aspergillosis;    Immunocompetence;    Mediastinal Neoplasms;    Heart Neoplasms;   

DOI  :  10.4046/trd.2014.77.1.28

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

We report a case of invasive pulmonary aspergillosis invading the mediastinum and the left atrium. A 70-year-old woman was hospitalized for dyspnea. She had been well controlled for her diabetes mellitus and hypertension. The chest X-ray disclosed mediastinal widening, and the computed tomography scan of the chest showed that there was a large mediastinal mass and this lesion extended into the left atrium and right bronchus. The cardiac echocardiography showed that a huge mediastinal cystic mass compressed in the right atrium and a hyperechoic polypoid lesion in the left. The pathology from the bronchoscopic biopsy observed abundant fungal hyphae which was stained with periodic acid-Schiff and Gomori's methenamine silver. Despite the treatment with antifungal agents, she died from cardiac tamponade after three months. Invasive pulmonary aspergillosis, which involves the mediastinum and the heart, is very rare in immunocompetent patients.

【 授权许可】

CC BY-NC