A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis with Bronchiolitis Obliterans Organizing Pneumonia-like Variant in Ulcerative Colitis

Tuberculosis and Respiratory Diseases

article

Shin Myung Kang¹  Young Rock Jang¹  Hyun-Hwa Yoon¹  Suji Kim¹  Eun Young Kim²  Seung Yeon Ha³  Jeong-Woong Park¹ 

[1] Department of Pulmonary and Critical Care Medicine, Gachon University Gil Hospital, Incheon;Department of Radiology, Gachon University Gil Hospital, Incheon;Department of Pathology, Gachon University Gil Hospital, Incheon

关键词: Balsalazide;    Wegener Granulomatosis;    Colitis;    Ulcerative;   

DOI  :  10.4046/trd.2012.72.3.323

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely rare. Here, we report a patient with ulcerative colitis on balsalazide presenting respiratory symptoms and multiple pulmonary nodules from a chest radiography that was pathologically diagnosed with a limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant. To our knowledge, this is the first report of a balsalazide-induced limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant.

【 授权许可】

CC BY-NC