Caplan's Syndrome Presenting as Multiple Pulmonary Nodules.

Tuberculosis and Respiratory Diseases

article

Lee, Sang Kook¹  Lee, Sang Hoon¹  Kim, Song Yee¹  Lee, Woo Kyung¹  Shin, Dong Ho¹  Bang, Woo Dae¹  Noh, Song Mi¹  Shim, Hyo Sup³  Park, Byung Hoon¹  Lee, Kyung Jong¹  Park, Moo Suk¹  Kim, Young Sam¹  Chang, Joon¹  Kim, Se Kyu¹  Kang, Young Ae¹ 

[1] Departments of Internal Medicine Yonsei University College of Medicine;The Institute of Chest Diseases, Yonsei University College of Medicine;Departments of Yonsei University College of Medicine

关键词: Caplan Syndrome;    Multiple Pulmonary Nodules;    Arthritis;    Rheumatoid;   

DOI  :  10.4046/trd.2011.70.2.150

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

We report a case of Caplan's Syndrome, which presented as multiple pulmonary nodules. A 58-year-old male was admitted to hospital due to multiple pulmonary nodules. In addition, the patient presented with multiple arthritis, and dyspnea on exertion. Rheumatoid arthritis had been diagnosed 35 years ago. The patient had worked as a stonemason for 20 years. Computed Tomography (CT) revealed numerous well-defined tiny nodules scattered in both lungs, which was suspicious of miliary tuberculosis or malignancy. The patient was started on antituberculous medications and referred to our hospital. First, a transbronchial lung biopsy was performed, which showed no evidence of granuloma. It was our opinion that the biopsy was insufficient, and a follow-up video-associated thoracoscopy was performed. The pathological report determined necrotizing granulomatous inflammation and silicosis on background. According to imaging studies, pathologic reports, and clinical symptoms, we concluded that the patient had Caplan's syndrome. We controlled his rheumatic medications, and instructed him to avoid exposure to hazardous dust.

【 授权许可】

CC BY-NC