Tuberculosis and Respiratory Diseases | |
Characteristics of Difficult to Treat Asthma in Korea. | |
article | |
Yoo, Kwang Ha1  Lee, Kwan Ho2  Uh, Soo Taek3  Park, Yong Bum4  Rhee, Yang Keun5  Oh, Yeon Mok6  | |
[1] Department of Internal Medicine, Konkuk University College of Medicine;Department of Internal Medicine, Yeungnam University College of Medicine;Department of Internal Medicine, Soonchunhyang University College of Medicine;Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine;Department of Internal Medicine, Chonbuk National University College of Medicine;Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine | |
关键词: Asthma; Therapeutics; Korea; Adrenal Cortex Hormones; Comorbidity; | |
DOI : 10.4046/trd.2010.69.5.361 | |
学科分类:医学(综合) | |
来源: The Korean Academy of Tuberculosis and Respiratory Diseases | |
【 摘 要 】
Background: Difficult-to-treat asthma afflicts a small percentage of the asthma population. However, these patients remain refractory to treat, and account for 40% to 50% of the health costs of asthma treatment, incurring significant morbidity. We conducted a multi-center cross-sectional study to characterize difficult-to-treat asthma in Korea. Methods: Subjects with difficult-to-treat asthma and subjects with controlled asthma were recruited from 5 outpatient clinics of referral hospitals. We reviewed medical records of previous 6 months and obtained patient-reported questionnaires composed of treatment compliance, asthma control, and instruments for stress, anxiety, and depression. Results: We recruited 21 subjects with difficult-to-treat asthma and 110 subjects with controlled asthma into the study. The subjects with difficult-to-treat asthma were associated with longer treatment periods, more increased health care utilization, more medication (oral corticosteroids, number of medication), and more anxiety disorder compared to those of well-controlled asthmatics. There was no difference in age, gender, history of allergy, serum IgE, blood eosinophil count, or body mass index between the 2 groups. Conclusion: Difficult-to-treat asthma is characterized by increased health care utilization and more co-morbidity of anxiety.
【 授权许可】
CC BY-NC
【 预 览 】
Files | Size | Format | View |
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RO202106050003829ZK.pdf | 359KB | download |