The First Case of Novel Influenza A (H1N1) Fatality in Korea.

Tuberculosis and Respiratory Diseases

article

Seol, Hee Yun¹  Eom, Jung Seop¹  Kim, Mi Hyun¹  Cho, Woo Hyun¹  Kim, Ji Eun¹  Kim, Ki Uk¹  Jeon, Doo Soo¹  Park, Hye Kyung¹  Kim, Yun Seong¹  Lee, Min Ki¹  Park, Soon Kew¹ 

[1] Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine

关键词: Influenza A Virus;    H1N1 Subtype;    Pneumonia;    Viral;    Respiratory Insufficiency;    Death;   

DOI  :  10.4046/trd.2010.68.6.350

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Here we report the first fatality caused by H1N1 influenza virus infection with acute respiratory distress syndrome in Korea. A 55-year-old man presented at our emergency department with dyspnea, fever, diffuse myalgia and malaise. Bilateral lung air-space consolidation was detected on his initial chest radiograph combined with severe hypoxemia. He was supported by mechanical ventilation and treated with antibiotics. A nasopharyngeal aspirate was positive for influenza A rapid antigen and oseltamivir was started on day 3 of admission. The nasal swab sample was positive for influenza H1N1 virus by real-time reverse-transcriptase polymerase chain reaction. Despite aggressive treatment, he had refractory hypoxemia and uncontrolled septic shock. On day 5 of admission he went into cardiac arrest and expired.

【 授权许可】

CC BY-NC