A meta-analysis to estimate the incidence of thromboembolism in hospitalized COVID-19 patients

AIMS Medical Science

article

Ayema Haque¹  Areeba Minhaj¹  Areeba Ahmed¹  Owais Khan¹  Palvisha Qasim¹  Hasan Fareed¹  Fatima Nazir¹  Ayesha Asghar¹  Kashif Ali¹  Sobia Mansoor¹ 

[1] Department of Internal Medicine, Dow University of Health Sciences

关键词: COVID-19;    SARS-CoV-2;    thromboembolism;    meta-analysis;    pulmonary embolism;    stroke;    myocardial infarction;    deep venous thrombosis;    ;   

DOI  :  10.3934/medsci.2020020

来源: American Institute of Mathematical Sciences

【 摘 要 】

Coronavirus disease 2019 (COVID-19) is associated with an increased risk of venous and arterial thrombosis in patients. Numerous studies have been conducted on COVID-19 and its association with thromboembolism is well known. We conducted a meta-analysis to find out the incidence of thromboembolism in hospitalised patients with COVID-19 to provide more generalized results. A systematic literature search was conducted in PubMed and SCOPUS to find observational studies reporting outcomes of interest. Amongst the studied thromboembolic events, the meta-analysis showed the prevalence of pulmonary embolism (PP: 12.4% [7.2%, 18.6%]; I2 = 97.23%) to be the highest. It was followed by deep vein thrombosis (PP: 8.6% [4.2%, 14.3%]; I2 = 97.52%), myocardial infarction (PP: 2.3% [0.2%, 11.2%]; I2 = 99.3%), and stroke (PP: 1.2% [0.8%, 1.6%]; I2 = 65.09%). The results of this analysis further warrant the timely and appropriate use of pharmacological thromboprophylaxis and identification of risk factors in hospitalized COVID-19 patients.

【 授权许可】

CC BY