Breast Cancer Risk Factors in Patients With Endometriosis

Archives of Breast Cancer

article

Bita Eslami¹  Sadaf Alipour²  Nafsa Khazaei³  Mahdi Sepidarkish⁴  Ashraf Moini⁵ 

[1] Breast Disease Research Center (BDRC), Tehran University of Medical Sciences;Department of Surgery, Arash Women's Hospital, Tehran University of Medical Sciences;Department of Microbiology, Tehran University of Medical Sciences;Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR;Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Iran AND Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Iran AND Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine

关键词: Endometriosis;    Revised: breast cancer;    risk factor;    laparoscopy;   

DOI  :  10.19187/abc.20185276-80

学科分类：社会科学、人文和艺术（综合）

来源: Kaviani Breast Disease Institute

【 摘 要 】

Background: Endometriosis is a common chronic inflammatory, estrogen-dependent disease with characteristics similar to cancer. Epidemiological studies of the association between endometriosis and breast cancer have yielded inconsistent results. The present study aimed to investigate the association between endometriosis and breast cancer risk factors. Methods: This case-control study (with 222 persons in each group) was conducted in Arash Women's Hospital from 2014 to 2017. Women with laparoscopically proven endometriosis were considered as cases. Controls were selected from women who had previous laparoscopic surgery due to any reason, and the absence of endometriosis was confirmed in them. Results: Multivariate logistic regression analysis by considering the risk factors (age, body mass index, gravidity, age at first pregnancy, age at menarche, history of breast-feeding, history of oral contraceptive and hormone use, history of miscarriage and induced abortion, breast cancer in first-degree relatives, and physical activity) revealed that endometriosis was positively association with age at first pregnancy (OR = 1.16, 95% CI: 1.08-1.25; P

【 授权许可】

CC BY-NC