Sleep Induced Hypoxemia in Chronic Obstructive Pulmonary Disease

Journal of Nepal Medical Association

article

Jing Zhang¹  Yan Wang¹  Jing Feng¹  Xin Sun² 

[1] Respiratory Department of Tianjin Medical University General Hospital;Respiratory Department ofTianjin Haihe Hospital

关键词: chronic obstructive pulmonary disease;    polysomnography;    rapid eye movement;    sleep-induced hypoxemia.;   

DOI  :  10.31729/jnma.2285

学科分类：社会科学、人文和艺术（综合）

来源: Nepal Medical Association since

【 摘 要 】

Chronic obstructive pulmonary disease is a leading cause of morbidity and mortality worldwide.Sleep-induced hypoxemia is defined as “an SpO2 (oxyhemoglobin saturation) during sleep of 30% of total sleep time with anSpO2 of < 90%” in subject with a baseline awake SpO2 of ≥ 90%. Patients with moderate or severeCOPD run a high risk of developing SIH mainly because of alveolar hypoventilation and ventilationperfusionmismatch. Compared to their non-SIH brethren, SIH COPD patients have greater degreesof pulmonary hypertension and cor pulmonale, require more frequent hospitalizations, and sustainhigher mortality rates. And the necessity of treatment of isolated SIH in COPD has been debatedfor years. In this mini review, the definition, reasons, prevalence, clinical significance and treatmentapproaches of SIH in COPD are summarized.

【 授权许可】

CC BY