Serum Squamous Cell Carcinoma Antigen and Its Application in Cervical Cancer Patients

Thai Journal of Obstetrics and Gynaecology

article

Chuenkamon Charakorn¹ 

[1] Department of Obstetrics and Gynaecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University

关键词: cervical cancer;    SCC-Ag;   

DOI  :  10.14456/tjog.2017.29

学科分类：社会科学、人文和艺术（综合）

来源: The Royal Thai College of Obstetricians and Gynaecologists

【 摘 要 】

Cervical cancer is the second most common female cancer in Thailand. The treatment depends on the stages of disease. Serum squamous cell carcinoma antigen (SCC-Ag) produces through squamous formation of cervical squamous epithelium and increased during the neoplastic transformation. However, it is not organ specific. In healthy women, serum SCC-Ag is found at a concentration of less than 1.9 μg/L. The cervical cancer clinical utilities of serum SCC-Ag reported in the literatures comprised of the indicative of pelvic or paraaortic lymph node metastases at the pretreatment evaluation period, the prediction of prognosis, the monitor the treatment response and the detection of early recurrence. With the limitation in health care resources of Thailand, raising of serum SCC-Ag also reminds the physician about distant recurrence of disease. Moreover, the detection of asymptomatic recurrence may be associated with prolonged survival.

【 授权许可】

CC BY-NC-ND