期刊论文详细信息
Thai Journal of Obstetrics and Gynaecology
Birth Weight/ Placental Weight Ratios: Does the association differ between early- and late-onset preeclampsia?
article
Podjanee Phadungkiatwattana1  Songphol Puttasiri1 
[1] Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University
关键词: preeclampsia;    placenta;    birth;    weight;    early onset;    late onset;   
DOI  :  10.14456/tjog.2019.16
学科分类:社会科学、人文和艺术(综合)
来源: The Royal Thai College of Obstetricians and Gynaecologists
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【 摘 要 】

Objectives:  Early- and late-onset preeclampsia (PE) may differ in pathophysiology and this can beObjectives:  Early- and late-onset preeclampsia (PE) may differ in pathophysiology and this can be reflcted in differences in birth weight/placental weight (BW/Pl) ratios. Therefore, we compared BW/Pl ratios of births with early- and those with late-onset PE. Materials and Methods:  The retrospective descriptive study included all hospital-based singleton births of 24-43 weeks’ gestation between January 2007 and December 2016. A total of 51,940 pregnant women were divided into three groups: early-onset PE, late-onset PE, and pregnant women without PE. Birth weight/placental weight were compared among 3 groups. Results:  The mean (± standard deviation; SD) BW/Pl ratios were signifiantly different in early-onset PE and late-onset PE compared with the control group (3.91 ± 0.93 in early-onset PE, 4.85 ± 0.91 in late-onset PE and 5.17 ± 0.90 in the control group, p < 0.001).  The factors signifiantly associated with BW/Pl ratios were race, infant gender, diabetes mellitus (DM), gestational age at delivery, early-onset PE, late-onset PE, small for gestational age (SGA) and large for gestational age (LGA). After adjustment for DM, gestational age at delivery, late-onset PE, SGA and LGA, the BW/Pl ratio was still associated signifiantly more with early-onset PE than with late-onset PE. Conclusion:  The BW/Pl ratios of preeclamptic women differed between early- and late-onset PE, and that early-onset PE may be commonly associated with placental efficiency.  This suggests that preeclampsia consists of several different processes manifesting as a single disease.

【 授权许可】

CC BY-NC-ND   

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