Challenges and perspectives in the multidisciplinary management of well-differentiated lung neuroendocrine tumours: a case report

Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche

article

Tindara Franchina¹  Alessandro Russo¹  Giuseppina RR Ricciardi¹  Vincenzo Adamo¹ 

[1] Dipartimento di Patologia Umana, Università di Messina U.O.C. Oncologia Medica

关键词: Neuroendocrine tumours;    carcinoids;    multidisciplinary management;   

DOI  :  10.6092/1828-6550/APMB.105.1.2017.A3

学科分类：农业科学（综合）

来源: Accademia Peloritana dei Pericolanti

【 摘 要 】

Neuroendocrine tumours of the lung represent a distinct subgroup of primary lung neoplasms, characterized by particular morphologic, ultrastructural, immunohistochemical and molecular peculiarities and different biological behavior. A detailed pathological diagnosis including immunohistochemistry, Ki-67, mitotic rate and necrosis status can be helpful to identify the different subtypes. The optimal management of advanced well-differentiated lung neuroendocrine tumors is still debated and can be very challenging for the clinician. Currently, no established therapeutic algorithm exists for patients with unresectable or metastatic typical carcinoids and atypical carcinoids. To highlight the importance of a multidisciplinary management we report the case of a patient affected by unresectable lung neuroendocrine tumors, who has benefited from integration strategy, resulting in complete surgical excision of the tumour.

【 授权许可】

CC BY