Hepatitis C virus infection and global kidney health: the consensus proceedings of the International Federation of Kidney Foundations

African Journal of Nephrology

article

Gamal Saadi¹  Kamyar Kalantar-Zadeh¹  Piero Almasio¹  Gloria Ashuntantang¹  Rashad Barsoum¹  Annette Bruchfeld¹  Wahid Doss¹  Hussein El-Fishawy¹  Maissa El Raziky¹  Magdy El-Serafy¹  Fabrizio Fabrizi¹  Hany Hafez¹  May Hassaballa¹  Mona Hammady¹  Hussein Sheishaa¹  Tarek Samy Abdelaziz¹  Ifeoma Ulasi¹  Elena Zakharova¹  Michel Jadoul¹ 

[1] Department of Renal medicine –Kasr Alainy University Hospitals

关键词: hepatitis C virus infection;    Africa;    chronic kidney disease.;   

DOI  :  10.21804/23-1-4210

学科分类：数学（综合）

来源: African Association of Nephrology

【 摘 要 】

Hepatitis C virus (HCV) infection is an important cause of major morbidities including chronic liver disease, liver cancer, acute kidney injury and chronic kidney disease (CKD). Among patients with kidney disease who have HCV infection, the clinical outcomes are worse. The prevalence of HCV infection is exceptionally high among dialysis and kidney transplant patients throughout the globe. It is estimated that 5% to 25% or more of dialysis-dependent patients are affected. Almost half of all deaths in CKD patients, including HCV-infected patients, are due to cardiovascular disease, and HCV-infected patients have higher mortality. Given the importance and impact of the HCV epidemic on global kidney health, and the status of Egypt as the nation with the highest prevalence of HCV infection in the world along with its initiatives to eradicate HCV, the International Federation of Kidney Foundations convened a consensus conference in Cairo in December 2017. This article reflects the opinions and recommendations of the contributing experts and reiterates that, with the current availability of highly effective and well tolerated pharmacotherapy, CKD patients should be given priority for the treatment of HCV, as an important step towards the World Health Organization’s goal of eliminating viral hepatitis as a public health problem by 2030.

【 授权许可】

CC BY