The Diagnostic Role of Hyperbilirubinemia in Complicated and Non -complicated Appendicitis.

Albanian Journal of Trauma and Emergency Surgery

article

Valon Zejnullahu¹  Rozalinda Isjanovska²  Besnik Bicaj¹  Vjosa A. Zejnullahu¹  Astrit R. Hamza¹  Viktoria Caloska Ivanova³ 

[1] University Clinical Centre of Kosovo;Agency for Quality and Accreditation of Healthcare Organizations;University Clinic of Gastrohepatology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje

关键词: acute appendicitis;    total/direct bilirubin;    appendectomy;    examination;    clinical approach;    Alvarado score;    ;   

DOI  :  10.32391/ajtes.v2i2.14

学科分类：社会科学、人文和艺术（综合）

来源: Albanian Society for Trauma and Emergency Surgery

【 摘 要 】

Background: Acute appendicitis is one of the most frequent causes of abdominal pain. Early diagnosis is the key to success for the surgeon, followed by the treatment with operation or conservative treatment as a new approach, before the stage of gangrenous appendicitis or perforation occurs.Aim: This study aims to establish he role of hyperbilirubinemia as a laboratory marker in prediction of acute appendicitis in the early diagnosis.Materials and methods: This is a cross-sectional study; it included 201 patients admitted in the emergency ward with suspicion for acute appendicitis. All patients that participated in this study have been subject to appendectomy. The blood samples were taken from all patients in order to analyze the level of total/direct bilirubin.Results: The study samples of 201 patients consisted of 67.7% with complicated appendicitis and 32.3% with non-complicated appendicitis. The sensitivity, specificity, PPV, NPV for laboratory marker, as predictor for complicated vs non-complicated cases of appendicitis was as follows: Total bilirubin; specificity (72.3%), sensitivity (54.4%), PPV (80.4%), NPV (43.1%),Conclusion: Elevation of total/direct bilirubin level in patients with clinical signs of acute appendicitis might predict the stage of acute appendicitis, such prediction may help surgeons to provide accurate treatment of the disease without delay in the diagnosis. This accuracy can be further supplemented by using Alvarado scoring model during the clinical approach.

【 授权许可】

CC BY-NC