Pemberian ekstrak air buah sawo (Manilkara zapota L.) menurunkan kadar glukosa darah tikus (rattus norvegicus) diabetes mellitusDOI : 10.21927/ijnd.2015.3(3).180-186 | Abstract views : 867 times

Jurnal Gizi dan Dietetik Indonesia

article

Effatul Afifah¹ 

[1] Program Studi S1 Ilmu Gizi, Universitas Alma Ata

关键词: diabetes mellitus;    sapodilla extract water;    blood glucose;    ekstrak air buah sawo;    glukosa darah;   

DOI  :  10.21927/ijnd.2015.3(3).180-186

来源: Alma Ata University Press

【 摘 要 】

Background : Diabetes mellitus (DM) is a chronic metabolic problem disorder characterized by hyperglicemia which is caused by insulin deficiency produced by β-pancreas cells, thus causing abnormalities of carbohydrate, protein, and fat metabolism, and tend to cause complications. Objectives : To know the effect of sapodilla extract water on blood glucose level of diabetic induce mice. Methods : This was an experimental study with pre-post control group design. Sapodilla extract water (EABS) was fed to group of mice with alloxan diabetes induction. Twenty four DM induced mice were separated into 4 groups, e.g. control without and with medication of glibenclamide, EABS 1 (treated with 3.6 mL/200 g body weight), and EABS 2 (treated with 7.2 mL/200 g body weight). Mice were then measured for their blood glucose level at the day of 3, 14, and 30. Results : EABS 1 and EABS 2 decreased blood glucose levels at week of 1st, 2nd, and 3rd after induction. The greatest reduction was shown by EABS 2 at the 3rd week. EABS decreased blood glucose level of mice induced DM and signifi cantly shown at glibenclamide group, followed by EABS 2 and EABS 1. Conclusions : EABS reduced blood glucose levels of diabetic mice and signifi cantly shown for glibenclamide group, followed by EABS 2 and EABS 1.

【 授权许可】

Unknown