Fibrous dysplasia: rapid malignant transformation into osteogenic sarcoma - A rare occurance

Journal of Pathology of Nepal

article

S Gon¹  B Majumdar¹  A Bhattacharyya¹  RN Bhattacharya² 

[1] Department of Pathology, RG Kar Medical College & Hospital;Department of Plastic & Reconstructive Surgery, RG Kar Medical College & Hospital

关键词: Fibrous dysplasia;    Malignant transformation;    Osteogenic sarcoma;   

DOI  :  10.3126/jpn.v2i4.6891

来源: Alma Ata University Press

【 摘 要 】

Malignant transformation of fibrous dysplasia is rare, occurring in less than 1% of cases with a mean lag period of 13.5 years. We report a case of Osteogenic Sarcoma with chondroid differentiation in a pre-existing Fibrous Dysplasia occurring within one year of surgical resection and without any history of exposure to radiation. To the best of our knowledge and extensive search of literature, malignant transformation of Fibrous Dysplasia in such a short period of time, and without history of radiation exposure has never been reported from India.

【 授权许可】

CC BY