Prevalence of dry eyes syndrome and retinopathy in diabetic patients and the association of glycosylated hemoglobin with retinopathy

Journal of Pathology of Nepal

article

Poojyashree Karki¹  Milesh Jung Sijapati²  Pragya Singh Basnet¹  Anjila Basnet¹ 

[1] Department of Ophthalmology, KIST Medical College Teaching Hospital;Department of Internal Medicine, KIST Medical College Teaching Hospital

关键词: Dry eye;    Diabetes;    Eyes;    HbA1C;    Retinopathy;    Tear film break up time;   

DOI  :  10.3126/jpn.v8i2.20887

来源: Alma Ata University Press

【 摘 要 】

Background: Diabetes is one of the most common leading causes of blindness in 20–74 year old persons. Recently, problems involving the ocular surface, dry eyes in particular, have been reported in diabetic patients. This study was performed to assess the prevalence of dry eyes syndrome and diabetic retinopathy and its association with HbA1c in diabetic patients.Materials and Methods: All the diabetic patients referred to Eye OPD were consecutively selected during the study period of three years. All the subjects were assessed by developed questionnaire; complete eye examination and Tear Film break up time (TBUT) test and Schirmer’s test. HbA1c was performed in all patients as advised by the physician and was entered in our records.Results: Of 304 subjects, 165 patients (54.3%) suffered from dry eyes syndrome. Although dry eyes syndrome was more common in female patients, this association was not significant. Diabetic Retinopathy was found in 154 patients (50.65%). Dry eyes syndrome was more frequent in diabetic patients with diabetic retinopathy. (P = 0.02). Compared with patients without diabetic retinopathy, those with diabetic retinopathy were more likely to have higher HbA1c (p<0.001). Conclusion: Diabetic retinopathy and dry eyes appear to have a common association like ageing.  Examination for dry eyes should be an integral part of the assessment of diabetic eye disease. In addition, high HbA1c level was an important factor associated with prevalence of Diabetic Retinopathy.

【 授权许可】

CC BY