The association between incidence and mortality of brain cancer and human development index (HDI): an ecological study

BMC Public Health

Hosein Mirshekarpour¹  Isan Darvishi²  Zaher Khazaei³  Batool Mirzaei⁴  Sayeed Maryam Bechashk⁵  Hasan Naemi⁶  Roghayeh Ershad Sarabi⁷  Ahmad Naghibzadeh-Tahami⁸  Farhad Iranmanesh⁹  Vahidreza Borhaninejad^1,10  Elham Goodarzi^1,11 

[1] Clinical Research Unit, Shafa Hospital, Kerman University of Medical Sciences, Kerman, Iran;Department Of Operating Room, Instructor Of Operating Room ,Shahrekord University Of Medical Sciences, Shahrekord, Iran;Department of Public Health, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran;Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Science, Kerman, Iran;Epidemiology, Social Determinants of Health Research Center, Research institute for Health Development, Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran;Iranian Research Center on Healthy Aging, Sabzevar University of Medical Sciences, Sabzevar, Iran;Medical Informatics Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran;Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran;Professor of Neurology, Stroke Fellowship, Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran;Social Determinants of Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran;Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran;

关键词: Incidence;    Mortality;    Brain Cancer;    Human development index;    World;   

DOI  :  10.1186/s12889-020-09838-4

来源: Springer

【 摘 要 】

BackgroundBrain cancer is a rare and deadly malignancy with a low survival rate. The present study aims to evaluate the epidemiology of brain cancer and its relationship with the human development index (HDI) worldwide.MethodsThis is an ecological study. The data on cancer incidence and cancer mortality was extracted from the World Bank for Cancer in 2018 (GLOBOCAN 2018). The incidence, mortality rate, and brain cancer distribution maps were drawn for different countries. We used correlation and regression tests to examine the association of incidence and mortality rates of brain cancer with HDI. The statistical analysis was carried out by Stata-14 and a significance level of 0.05 was considered.ResultsAccording to the results of Global Cancer Registry in 2018, there were 18,078,957 registered cases of cancer in both sexes, of which 29,681 were related to brain cancer. The highest incidence (102,260 cases, 34.4%) and mortality (77,815 cases, 32.3%) belonged to very high HDI regions. Results showed that incidence (r = 0.690, P < 0.0001) and mortality rates (r = 0.629, P < 0.001) of brain cancer are significantly correlated with HDI. We also observed a positive correlation between brain cancer incidence and Gross National Income (GNI) (r = 0.346, P < 0.001), Mean Years of Schooling (MYS) (r = 0.64, P < 0.001), TABLE (LEB) (r = 0.66, P < 0.001) and Expected Years of Schooling (EYS) (r = 0.667, P < 0.001). Results also revealed that mortality rate was significantly correlated with GNI (r = 0.28, P < 0.01), MYS (r = 0.591, P < 0.01), LEB (r = 0.624, P < 0.01), and EYS (r = 0.605, P < 0.01).ConclusionThe results of the study showed that the incidence and mortality of brain cancer in countries with higher HDI levels is higher than countries with lower HDI levels, so attention to risk factors and action to reduce it in countries with higher HDI levels in controlling this cancer in this Countries are effective.

【 授权许可】

CC BY