Genomics in the era of COVID-19: ethical implications for clinical practice and public health

Genome Medicine

Jeffrey P. Kahn¹  Debra Mathews²  Gail Geller³  Priya Duggal⁴  Chloe L. Thio⁵  Lisa L. Maragakis⁶  Brian T. Garibaldi⁷ 

[1] Berman Institute of Bioethics, Johns Hopkins University, Deering Hall, Room 202, 1809 Ashland Ave., 21205, Baltimore, MD, USA;Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., 21205, Baltimore, MD, USA;Berman Institute of Bioethics, Johns Hopkins University, Deering Hall, Room 202, 1809 Ashland Ave., 21205, Baltimore, MD, USA;Johns Hopkins University School of Medicine, Baltimore, MD, USA;Berman Institute of Bioethics, Johns Hopkins University, Deering Hall, Room 202, 1809 Ashland Ave., 21205, Baltimore, MD, USA;Johns Hopkins University School of Medicine, Baltimore, MD, USA;Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., 21205, Baltimore, MD, USA;Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., 21205, Baltimore, MD, USA;Johns Hopkins University School of Medicine, Baltimore, MD, USA;Johns Hopkins School of Medicine Hepatitis Center, 855 N. Wolfe St. Rangos Room 533, 21205, Baltimore, MD, USA;Johns Hopkins University School of Medicine, Baltimore, MD, USA;Johns Hopkins School of Medicine Infection Control, 600 N. Wolfe St., Osler 425, 21205, Baltimore, MD, USA;Johns Hopkins University School of Medicine, Baltimore, MD, USA;Johns Hopkins University School of Medicine Pulmonology, 5501 Hopkins Bayview Circle, 21224, Baltimore, MD, USA;

关键词: COVID-19;    Ethics;    Host genomics;   

DOI  :  10.1186/s13073-020-00792-9

来源: Springer

【 摘 要 】

Genomic studies of patients with COVID-19, or exposed to it, are underway to delineate host factors associated with variability in susceptibility, infectivity, and disease severity. Here, we highlight the ethical implications—both potential benefits and harms—of genomics for clinical practice and public health in the era of COVID-19.

【 授权许可】

CC BY