Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series

Virology Journal

Shengyun Wang¹  Qiaoyun Yan²  Li Jin²  Wei Gao²  Si Chen²  Kun Wang²  Feilong Wang²  Qian Guo²  Qiang Li²  Jing Hua²  Xiaodong Wu²  Rongzhang Chen²  Jingjing Lu²  Yanan He² 

[1] Department of Emergency and Critical Care Medicine, Changzheng Hospital, Second Military Medical University, 200082, Shanghai, China;Department of Pulmonary and Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, 200123, Shanghai, China;

关键词: Coronavirus disease;    COVID-19;    Arbidol;    Efficacy;    SARS-CoV-2;   

DOI  :  10.1186/s12985-020-01428-5

来源: Springer

【 摘 要 】

ObjectiveWe aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions.MethodsBasic clinical characteristics were described and the efficacy of Arbidol was evaluated based on gender, age, maximum body temperature of the patients.ResultsBasically, males had a higher risk of fever and more onset symptoms than females. Arbidol could accelerate fever recovery and viral clearance in respiratory specimens, particularly in males. Arbidol also contributed to shorter hospital stay without obvious adverse reactions.ConclusionsIn the retrospective COVID-19 cohort, gender was one of the important factors affecting patient's conditions. Arbidol showed several beneficial effects in these patients, especially in males. This study brought more researches enlightenment in understanding the emerging infectious disease.

【 授权许可】

CC BY