Validation of the Palliative Prognostic Index, Performance Status–Based Palliative Prognostic Index and Chinese Prognostic Scale in a home palliative care setting for patients with advanced cancer in China

BMC Palliative Care

Fangping Zhou¹  Xiangheng Dai²  Xiang Fang³  Ling Qin³  Yongzheng Bao³  Qiang Wu³  Jun Zhou³  Ziye Cao³  Sitao Xu³  Jing Tang³  Xueren Zhong³  Yan Wang⁴  Fengjuan Lu⁵  Mingcai Hu⁶  Yuzhen He⁷ 

[1] Department of Nursing, Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, China;Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China;Department of Spine Surgery, Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, China;Emergency rescue command center of Shaoguan city, Shaoguan, Guangdong, China;Hospice center of Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China;Hospice center of Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, China;Hospice center of Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, China;Department of Nursing, Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, China;

关键词: Validation;    Palliative prognostic index;    Performance status–based palliative prognostic index;    Chinese prognosis scale;    Advanced Cancer;    Home-based palliative care setting;   

DOI  :  10.1186/s12904-020-00676-0

来源: Springer

【 摘 要 】

BackgroundThe predictive value of the prognostic tool for patients with advanced cancer is uncertain in mainland China, especially in the home-based palliative care (HPC) setting. This study aimed to compare the accuracy of the Palliative Prognostic Index (PPI), the Performance Status–Based Palliative Prognostic Index (PS-PPI), and the Chinese Prognosis Scale (ChPS) for patients with advanced cancer in the HPC setting in mainland China.MethodsPatients with advanced cancer admitted to the hospice center of Yuebei People’s Hospital between January 2014 and December 2018 were retrospectively calculated the scores according to the three prognostic tools. The Kaplan-Meier method was used to compare survival times among different risk groups. Receiver operating characteristic curve analysis was used to assess the predictive value. The accuracy of 21-, 42- and 90-day survival was compared among the three prognostic tools.ResultsA total of 1863 patients were included. Survival time among the risk groups of all prognostic tools was significantly different from each other except for the PPI. The AUROC of the ChPS was significantly higher than that of the PPI and PS-PPI for 7-, 14, 21-, 42-, 90-, 120-, 150- and 180-day survival (P < 0.05). The AUROC of the PPI and PS-PPI were not significantly different from each other (P > 0.05).ConclusionsThe ChPS is more suitable than the PPI and PS-PPI for advanced cancer patients in the HPC setting. More researches are needed to verify the predictive value of the ChPS, PPI, and PS-PPI in the HPC setting in the future.

【 授权许可】

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