Specific populations of urinary extracellular vesicles and proteins differentiate type 1 primary hyperoxaluria patients without and with nephrocalcinosis or kidney stones

Orphanet Journal of Rare Diseases

Felicity T. Enders¹  Nicholas B. Larson¹  Stanislav V. Yuzhakov²  Andrew D. Rule³  Dawn S. Milliner³  Sanjay Kumar³  John C. Lieske⁴  Muthuvel Jayachandran⁵ 

[1] Biomedical Statistics and Bioinformatics, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Division of Hematology Research, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Department of Physiology and Biomedical Engineering, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Division of Nephrology and Hypertension, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Division of Nephrology and Hypertension, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Department of Laboratory Medicine and Pathology, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Division of Nephrology and Hypertension, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Division of Hematology Research, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;Department of Physiology and Biomedical Engineering, College of Medicine and Science, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA;

关键词: Microvesicles;    Exosomes;    Urinary vesicles;    Urinary proteins;    Oxalate;    Renal calcification;    Urinary stone disease;   

DOI  :  10.1186/s13023-020-01607-1

来源: Springer

【 授权许可】

CC BY