Association between anterior bone loss and anterior heterotopic ossification in hybrid surgery

BMC Musculoskeletal Disorders

Beiyu Wang¹  Kangkang Huang¹  Ying Hong¹  Tingkui Wu¹  Junbo He¹  Hao Liu¹  Chen Ding¹ 

[1] Department of Orthopedic Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Rd, 610041, Chengdu, China;

关键词: Anterior bone loss;    Anterior heterotopic ossification;    Hybrid surgery;   

DOI  :  10.1186/s12891-020-03664-w

来源: Springer

【 摘 要 】

BackgroundHybrid surgery (HS) has become an alternative procedure for the treatment of multilevel cervical degenerative disc disease with satisfactory outcomes. However, some adverse outcomes have recently emerged, such as heterotopic ossification (HO) and anterior bone loss (ABL). Furthermore, HO was found mostly located in the posterior and lateral of the cervical intervertebral disc space. The mechanism of anterior heterotopic ossification (AHO) formation may be different, and its relationship with ABL was uncertain.MethodsRadiographical and clinical outcomes of ninety-seven patients who had undergone contiguous two-level HS between December 2010 and December 2017 and with a minimum of 2-year follow-up were analyzed. Postoperative radiographs were evaluated and compared to the initial postoperative films to determine the incidence of ABL and AHO.ResultsThe overall incidence rate of ABL was 44.3% (43/97). It was identified in 70.6% of AHO cases (33.3% mild, 41.7% moderate, 25.0% severe) and 38.8% of non-AHO cases (38.7% mild, 45.2% moderate, 16.1% severe). A significant association between ABL and AHO occurrence was found (P = 0.016). There was no significant difference in prosthesis–endplate depth ratio or disc space angle change between the AHO group and the non-AHO group (P > 0.05). Compared with data preoperatively, clinical outcome scores significantly improved after surgery in both the AHO and non-AHO groups, with no significant differences between the two groups (P > 0.05).ConclusionABL was common in HS, and it related to AHO. The formation of AHO could be an integral part of postoperative bone remodeling, as well as ABL.

【 授权许可】

CC BY