Liver resections for metastasis: surgical outcomes of a single center academic institution

BMC Surgery

Vighnesh Vetrivel Venkatasamy¹  Danilo Saavedra Bussyguin²  Eduardo DaCás²  Raphaella Ferreira³  Phillipe Abreu⁴  Luiz Arnaldo Szutan⁵  Flávio Daniel Saavedra Tomasich⁶ 

[1] Department of Surgery, University of Miami, Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL, USA;Erasto Gaertner Hospital, Centro de Projetos de Estudo E Pesquisa (CEPEP), Curitiba, PR, Brazil;Erasto Gaertner Hospital, Centro de Projetos de Estudo E Pesquisa (CEPEP), Curitiba, PR, Brazil;Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Cirurgia, Área de Fígado e Hipertensão Portal, São Paulo, SP, Brazil;Erasto Gaertner Hospital, Centro de Projetos de Estudo E Pesquisa (CEPEP), Curitiba, PR, Brazil;Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Cirurgia, Área de Fígado e Hipertensão Portal, São Paulo, SP, Brazil;Department of Surgery, University of Miami, Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL, USA;Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Cirurgia, Área de Fígado e Hipertensão Portal, São Paulo, SP, Brazil;Hospital Erasto Gaertner, Curitiba, PR, Brazil;

关键词: Liver resection;    Hepatectomy;    Liver tumors;    Liver metastases;    Postoperative complications;   

DOI  :  10.1186/s12893-020-00920-7

来源: Springer

【 摘 要 】

BackgroundHepatic metastasis are frequent and liver resection may be an option for some cases, despite the high complexity of the procedure and the possibility of postoperative complications.MethodsThis retrospective comparative descriptive study aims to evaluate a series of 86 consecutive liver resections (LRs) performed for the treatment of metastatic liver tumors, comparing the results between patients undergoing major and minor LR. All patients submitted to LR from October 2010 to July 2015 at the Erasto Gaertner Hospital in Curitiba-PR were included. Quantitative numerical variables were analyzed with the Student t-test. The nonparametric Mann–Whitney U test was used for numerical variables of non-normal distribution. Categorical variables were analyzed with the Chi-square test with Fisher's correction. The data were analyzed with the SPSS 23.0 and STATA 15 programs, being p < 0.05 considered statistically significant.ResultsEighty-six LR were performed, 56 cases by colorectal metastasis. The major LR corresponded to 68 cases, with 13.2% of Clavien-Dindo III–V complications and 2.9% of reoperation rate. Eighteen minor LR were performed and one patient had a postoperative complication requiring reoperation.ConclusionPreoperative elevation of transaminases and jaundice negatively influence surgical outcomes in patients undergoing LR. Tumors greater than 3 cm presented worse postoperative survival. Major LR did not significantly increase the surgical morbidity rate.Institutional Review Board registration1.122.319/2015

【 授权许可】

CC BY