Orbital mucormycosis in immunocompetent children; review of risk factors, diagnosis, and treatment approach

BMC Infectious Diseases

Bijan Khademi¹  Mohammad Javad Ashraf²  Anahita Sanaei Dashti³  Gholamreza Pouladfar³  Seyedeh Sedigheh Hamzavi³  Ali Amanati³  Parisa Badiee³  Hamide Barzegar⁴  Ali Kashkooe⁴  Mohamad Bagher Abtahi⁴ 

[1] Department and Research Center of Otolaryngology, Head and Neck Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran;Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran;Shiraz University of Medical Sciences, Namazi Hospital, 7193711351, Zand Ave, Shiraz, Iran;

关键词: Mucormycosis;    Orbital;    Immunocompetent;    Children;   

DOI  :  10.1186/s12879-020-05460-2

来源: Springer

【 摘 要 】

BackgroundOrbital mucormycosis is a rare but potentially severe and troublesome invasive fungal infection that could be occurred even in healthy individuals. The initial clinical presentation is similar to bacterial pre-septal or septal cellulitis, especially in early stages.Case presentationHerein, we describe the successful management of a series of five cases presenting with orbital mucormycosis in previously healthy children.ConclusionsOrbital mucormycosis is extremely rare in healthy children and maybe life-threatening when diagnosis delayed given a similar clinical presentation with bacterial septal cellulitis. Intravenous antifungal therapy with amphotericin B and timely surgical drainage is live-saving.

【 授权许可】

CC BY