Effect of Bacillus velezensis to substitute in-feed antibiotics on the production, blood biochemistry and egg quality indices of laying hens

BMC Veterinary Research

Anam Khalid¹  Qian Hu¹  Miao Ye¹  Ru Yang¹  Binghong Dai¹  Chunjie Wei¹  Zaigui Wang¹  Hengwei Cheng² 

[1]College of Life Science, Anhui Agricultural University, No. 130, Changjiang Road, 230036, Hefei, Anhui, The People’s Republic of China

[2]Department of Animal Science, Purdue University, 270 S, Russell ST, 47907, West Lafayette, IN, USA

关键词: Bacillus velezensis;    Production performance;    Egg quality;    Serum biochemical index;   

DOI  :  10.1186/s12917-020-02570-6

来源: Springer

【 摘 要 】

BackgroundThe excessive use of antibiotics in the livestock feed industry caused inevitable side effects of microbial resistance. Besides this residual antibiotics in animal-derived foodstuff imposed serious health problems for humans. So this study aimed to investigate the potential use of Bacillus velezensis to substitute antibiotics for poultry production. A total of 468, 49-week-old Hy-Line Brown chickens, were randomly divided into four groups the control group (regular diet), experiment group I (0.1% B. veleznesis), experiment group II (0.2% B. veleznesis), and antibiotic group (50 mg/kg flavomycin), with three replicates per group and trial period consisted on 42 days.ResultsThe results showed that, compared with the control group, the average egg production rate and daily feed intake of experimental groups I and II increased significantly (P < 0.05), while the average egg weight was increased in experimental group II as compared to (I) (P < 0.01). The feed conversion ratio was decreased (P > 0.05) in group (II) Egg quality parameters such as yolk weight of the experimental group II was increased, but that of the antibiotic group and experiment group I was decreased, neither significant (P > 0.05). Moreover, the eggshell strength, yolk color, albumen height, and Haugh unit were significantly increased (P < 0.05). Compared with the control group, probiotic groups can increase the progesterone and motilin (P > 0.05) but decrease the secretin and cholecystokinin in the blood plasma (P > 0.05).ConclusionsThis study suggested that B. velezensis can substitute in-feed-antibiotics and improved most of the study parameters significantly. Which suggested that B. velezensis has potential future application value to replace the feed antibiotics.

【 授权许可】

CC BY