Three-dimensional transthoracic echocardiographic evaluation of tricuspid regurgitation severity using proximal isovelocity surface area: comparison with volumetric method

Cardiovascular Ultrasound

Quan Li¹  Cuizhen Pan¹  Dehong Kong²  Wuxu Zuo²  Lili Dong²  Junbo Ge²  Xianhong Shu²  Beiqi Chen²  Yu Liu² 

[1] Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai, China;Shanghai Institute of Medical Imaging, Shanghai, China;Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai, China;Shanghai Institute of Medical Imaging, Shanghai, China;Shanghai Institute of Cardiovascular Diseases, Shanghai, China;

关键词: Three-dimensional echocardiography;    Tricuspid regurgitation;    Proximal isovelocity surface area;    Effective regurgitant orifice area;   

DOI  :  10.1186/s12947-020-00225-y

来源: Springer

【 摘 要 】

BackgroundThe quantification of tricuspid regurgitation(TR) using three-dimensional(3D) proximal isovelocity surface area (PISA) derived effective regurgitant orifice area (EROA) is feasible in functional TR. The aim of our study was to explore the diagnostic accuracy and utility of 3D PISA EROA in a larger population of different etiologies.MethodsOne hundred and seven patients with confirmed TR underwent 2D and 3D transthoracic echocardiography (TTE). 3D PISA EROA was calculated and EROA derived from 3D regurgitant volume (Rvol) was used as the reference.Results3D PISA EROA showed better correlation in primary TR than in functional TR(r = 0.897, P < 0.01). 3D PISA EROA differentiated severe TR with comparable accuracy in patients with primary and functional etiology (Z-value 16.506 vs 21.202), but with different cut-offs (0.49cm2 vs. 0.41 cm2). The chi-square value for incorporated clinical symptoms, positive echocardiographic results and 3D PISA EROA to grade severe TR was higher than only included clinical symptoms or incorporated clinical symptoms and positive echocardiographic results (chi-square value 137.233, P < 0.01).ConclusionTR quantification using 3D PISA EROA is feasible and accurate under different etiologies. It has incremental diagnostic value for evaluating severe TR.

【 授权许可】

CC BY