Ganoderma spore powder contains little triterpenoids

Chinese Medicine

Shao-Ping Li¹  Ling-Xiao Chen¹  Mei-Ting Liu¹  Jing Zhao¹ 

[1] State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China;

关键词: Ganoderma;    Triterpenoids;    Bionic extraction;    Artificial gastroenteric fluid;    HPTLC;    LC–QTOF–MS;   

DOI  :  10.1186/s13020-020-00391-1

来源: Springer

【 摘 要 】

BackgroundGanoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture.MethodsAfter testing sporoderm-broken rate, the triterpenoids in 12 batches of broken and unbroken Ganoderma spore powder (GSP) samples were compared with Ganoderma lucidum fruiting body (GL) by high performance thin-layer chromatography (HPTLC) and further verified by liquid chromatography coupled with electrospray ionization quadrupole-time-of-flight mass spectrometry (LC–QTOF–MS); meanwhile, the dissolution of triterpenoids after bionic extraction was also investigated by HPTLC.ResultsThe sporoderm-broken rate of all the broken GSP samples was over 85%. The relative peak area of triterpenoids in GSP samples were lower than 50% of that in fruiting body, and the dissolution of triterpenoids in artificial gastrointestinal fluid was lower than in methanol.ConclusionsThis study demonstrated that there were little triterpenoids in GSP. Triterpenoids in GSP also seldom be dissolved in artificial gastrointestinal fluid.

【 授权许可】

CC BY