SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report

BMC Pregnancy and Childbirth

Santiago Manuel Fernandez Manovel¹  Sergio Marcos Contreras¹  Fernando Diez Buron¹  Alejandro Garcia Rodriguez¹  Jose Miguel Marcos Vidal¹  Maria del Carmen Riveira Gonzalez²  Camino Fernandez Fernandez³ 

[1] Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071, City Leon, Spain;Department of Neurology, University Complex Hospital of Leon, 24071, City Leon, Spain;Department of Obstetrics and Gynaecology, University Complex Hospital of Leon, 24071, City Leon, Spain;

关键词: COVID-19;    Case-report;    Pregnancy;    Preeclampsia;    Neurological manifestations;   

DOI  :  10.1186/s12884-020-03275-2

来源: Springer

【 摘 要 】

BackgroundThere are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology.Case presentationA 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography.ConclusionThe authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy.

【 授权许可】

CC BY