Does cystic fibrosis constitute an advantage in COVID-19 infection?

Italian Journal of Pediatrics

Francesca Lucca¹  Marco Cipolli¹  Valentino Bezzerri¹  Sonia Volpi¹ 

[1] Cystic Fibrosis Center of Verona, Azienda Ospedaliera Universitaria Integrata, 37126, Verona, Italy;

关键词: Cystic fibrosis;    SARS-CoV-2;    Covid-19;    Azythromycin;    DNase;   

DOI  :  10.1186/s13052-020-00909-1

来源: Springer

【 摘 要 】

The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with severe pulmonary impairment in cystic fibrosis (CF). We would have therefore expected numerous cases of severe COVID-19 among the CF population. Surprisingly, we found that CF patients were significantly protected against infection by SARS-CoV-2. We discussed this aspect formulating some reasonable theories.

【 授权许可】

CC BY