Beyond Antibiotics: Photo/Sonodynamic Approaches for Bacterial Theranostics

Nano-Micro Letters

Jingliang Cheng¹  Jing Zhu¹  Xin Pang²  Gang Liu³  Dengfeng Li⁴ 

[1] Henan Key Laboratory of Functional Magnetic Resonance Imaging and Molecular Imaging, Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, People’s Republic of China;Henan Key Laboratory of Functional Magnetic Resonance Imaging and Molecular Imaging, Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, People’s Republic of China;State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics and Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 361102, Xiamen, People’s Republic of China;State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics and Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 361102, Xiamen, People’s Republic of China;State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics and Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 361102, Xiamen, People’s Republic of China;Amoy Hopeful Biotechnology Co., Ltd, 361027, Xiamen, People’s Republic of China;

关键词: Photodynamic therapy;    Sonodynamic therapy;    Theranostics;    Multidrug resistant;    Reactive oxygen species;   

DOI  :  10.1007/s40820-020-00485-3

来源: Springer

【 摘 要 】

tsRecent advances in bacterial theranostics using antimicrobial photo/sonodynamic therapy (aPDT/SDT) are summarized in this review.The inherent optical characteristics of photo/sonosensitizers facilely enable imaging diagnosis of bacterial infections.Reactive oxygen species as the killing effector of aPDT/SDT cause broad-spectrum damage for sterilization with no concern about antibiotic resistance.

【 授权许可】

CC BY