Intermediate outcomes of ab externo circumferential trabeculotomy and canaloplasty in POAG patients with prior incisional glaucoma surgery

BMC Ophthalmology

Yan Shi¹  Huaizhou Wang¹  Chen Xin¹  Ningli Wang¹  Ying Han²  Sarah Ziaei² 

[1] Beijing Tongren Eye center, Beijing Tongren Hospital, Capital medical university, Beijing, China;Department of Ophthalmology, University of California, San Francisco School of Medicine, San Francisco, California, USA;

关键词: Ab externo circumferential trabeculotomy;    Canaloplasty;    Primary open angle glaucoma;    Failed filtering glaucoma surgery;   

DOI  :  10.1186/s12886-020-01645-0

来源: Springer

【 摘 要 】

BackgroundTo compare the efficacy and safety of ab externo circumferential trabeculotomy (ECT) and canaloplasty on primary open angle glaucoma (POAG) patients with failed filtering surgery and intact schlemm’s canal (SC).MethodsWe conducted a retrospective chart review of POAG patients with failed filtering surgery and intact SC, who further received ECT and canaloplasty. The primary outcome measures were intraocular pressure (IOP) and the number of topical medications at each follow-up point. The secondary outcome compared the quantified success rate at1-year follow-up between the groups.ResultsTwenty-nine eyes were recruited in the ECT group and 19 eyes in canaloplasty group. The postoperative IOP and the number of topical medications decreased significantly in both groups (p < 0.001). The IOP at 3-month and 6-monthwas significantly lower in the ECT group (p = 0.039, p = 0.001) than in the canaloplasty group. Although the IOP at 12-mon was similar between the two groups, the number of topical medications was less in the ECT group (p = 0.040). Hyphema (72.4%) and ciliary body detachment (27.6%), which mainly resolve spontaneously, were two leading complications in the ECT group. The prevalence of hyphema was higher in ECT than in canaloplasty group (p < 0.001).ConclusionFor POAG with failed filtering surgery and intact SC, canaloplasty may be safer, whereas ECT presented better IOP control.Translational Relevance: Suggestions for surgical choice for POAG with failed filtering surgery.

【 授权许可】

CC BY