Association between device-measured physical activity and lumbar Modic changes

BMC Musculoskeletal Disorders

Juho-Antti Junno¹  Jesperi Saukkonen²  Juhani Määttä²  Marella Modarress Julin³  Raija Korpelainen⁴  Jaro Karppinen⁵  Petteri Oura⁶  Maisa Niemelä⁷  Jaakko Niinimäki⁷  Timo Jämsä⁸ 

[1] Center for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland;Cancer and Translational Medicine Research Unit, Faculty of Medicine, University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Department of Archaeology, Faculty of Humanities, University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Center for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Center for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland;Clinic of Physiatry, Oulu University Hospital (OYS), PO Box 21, 90029, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Center for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland;Department of Sports and Exercise Medicine, Oulu Deaconess Institute Foundation, PO Box 365, FI-90100, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Center for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland;Finnish Institute of Occupational Health, Aapistie 1, FI-90220, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Center for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland;Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, PO Box 5000, FI-90014, Oulu, Finland;Diagnostic Radiology, Oulu University Hospital (OYS), P.O. Box 10, FI-90029, Oulu, Finland;

关键词: Physical activity;    MVPA;    Device-based measurements;    Modic changes;    Lumbar spine;    Lumbar MRI;    Cohort study;    Vertebrae;    Skeletal health;   

DOI  :  10.1186/s12891-020-03638-y

来源: Springer

【 摘 要 】

BackgroundModic changes (MC) in the lumbar spine are considered one potential etiological factor behind low back pain (LBP). Multiple risk factors for MC have been suggested, including male gender, smoking and factors affecting hyperloading and mechanical stress such as high body mass index (BMI), strenuous physical work and high occupational and leisure-time physical activity (PA). So far, the effect of PA on the occurrence of MC has remained under debate due to contradictory findings. The purpose of this study was to investigate the possible association between device-measured moderate-to-vigorous PA (MVPA) (≥ 3.5 METs) and lumbar MC.MethodsThe study had 1374 participants from the Northern Finland Birth Cohort 1966. At the age of 46–48, PA was measured by a wrist-worn accelerometer, and lumbar magnetic resonance imaging (MRI) was carried out to determine MC. We analyzed the association between Type 1 (MC1) and Type 2 (MC2) MC and daily amount of MVPA (min/day) using sex-stratified logistic regression models before and after adjustment for BMI, socioeconomic status, smoking, and accelerometer wear time.ResultsAmong men, increased amount of MVPA was positively associated with any MC (adjusted OR corresponding to every 60 min/day of MVPA 1.41; 95% confidence interval (CI) 1.01 to 1.95) and MC2 (OR 1.54; 95% CI 1.14 to 2.08), but not with MC1 (OR 1.06; 95% CI 0.80 to 1.39). Among women, we only found a positive association between MVPA and MC1 before adjustments (unadjusted OR 1.42; 95% CI 1.06 to 1.92).ConclusionAmong men, increased amount of MVPA was associated with increased odds of any MC and particularly MC2. Among women, MVPA was not independently associated with MC.

【 授权许可】

CC BY