Burden of viral hepatitis caused by specific aetiologies in China, 1990–2016: findings from the GBD 2016

BMC Public Health

Man Li¹  Lu Zhang¹  Dian-wu Liu¹  Hao Zheng²  Zhuo-qun Wang³  Mai-geng Zhou³ 

[1] Department of Epidemiology and Statistic, Hebei Medical University, Shijiazhuang, 050017, Shijiazhuang, People’s Republic of China;Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, China;Hebei Chest Hospital, 050042, Shijiazhuang, People’s Republic of China;National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC, 100050, Beijing, People’s Republic of China;

关键词: Hepatitis;    Epidemiology;    Incidence;    Prevalence;    Disability-adjusted life year;   

DOI  :  10.1186/s12889-020-09533-4

来源: Springer

【 摘 要 】

BackgroundThe aim of this study is to quantify the burden caused by viral hepatitis in China from 1990 to 2016.MethodsData from the GBD 2016 study were extracted to calculate incidence, prevalence and disability-adjusted life years (DALYs). Trends in DALYs were assessed in 33 provinces/regions.ResultsFrom 1990 to 2016, the total incidence of hepatitis decreased by 88.5%. However, the prevalence of hepatitis (counts in thousands), increased by 37.6% from 153,856 (95% UI: 136,047-172,319) in 1990 to 211,721 (95% UI: 179,776-240,981) in 2016, with age-standardized prevalence rates changing slightly. The number and age-standardized rates of prevalence increased by 35.9 and 1.6% for hepatitis B, respectively, and by 81.8 and 30.4% for hepatitis C. Guangxi, Guangdong and Hainan had the highest age-standardized prevalence rates (≥16,500 per 100,000). Tibet, Qinghai and Gansu had the highest age-standardized DALYs rates (≥40 per 100,000). The largest absolute number of DALYs was observed in the 15–49 year age group in 2016. The highest rate of DALYs occurred in males aged 50–69 years and in females aged ≧70 years.ConclusionThe incidence and DALYs of viral hepatitis decreased dramatically from 1990 to 2016. However, the prevalence still remains at a high level, which may result in heavy burdens in the future.

【 授权许可】

CC BY