Food intake biomarkers for berries and grapes

Genes & Nutrition

M. T. Soria-Florido¹  M. Garcia-Aloy²  R. Llorach²  M. Ulaszewska³  F. Mattivi⁴  C. Manach⁵  N. Vázquez-Manjarrez⁶ 

[1] Biomarkers and Nutrimetabolomic Laboratory, Department of Nutrition, Food Sciences and Gastronomy, Food Technology Reference Net (XaRTA), Nutrition and Food Safety Research Institute (INSA-UB), Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain;Biomarkers and Nutrimetabolomic Laboratory, Department of Nutrition, Food Sciences and Gastronomy, Food Technology Reference Net (XaRTA), Nutrition and Food Safety Research Institute (INSA-UB), Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain;CIBER de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Barcelona, Spain;Fondazione Edmund Mach, Research and Innovation Centre Food Quality and Nutrition, Via Mach 1, 38010, San Michele all’Adige, Italy;Center for Omics Sciences, Proteomics and Metabolomics Facility – ProMeFa, IRCCS San Raffaele Scientific Institute, Milan, Italy;Fondazione Edmund Mach, Research and Innovation Centre Food Quality and Nutrition, Via Mach 1, 38010, San Michele all’Adige, Italy;Department of Cellular, Computational and Integrative Biology, CIBIO, University of Trent, Trento, Italy;Université Clermont Auvergne, INRAE, UNH, F-63000, Clermont–Ferrand, France;Université Clermont Auvergne, INRAE, UNH, F-63000, Clermont–Ferrand, France;Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark;Dirección de Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Slavador Zubiran, Mexico City, Mexico;

关键词: Grape;    Raisin;    Strawberry;    Blueberry;    Blackberry;    Cranberry;    Raspberry;    Blackcurrant;    Biomarkers;    Intake;   

DOI  :  10.1186/s12263-020-00675-z

来源: Springer

【 摘 要 】

Grapes and berries are two types of widely consumed fruits characterized by a high content in different phytochemicals. However, their accurate dietary assessment is particularly arduous, because of the already wide recognized bias associated with self-reporting methods, combined with the large range of species and cultivars and the fact that these fruits are popularly consumed not only in fresh and frozen forms but also as processed and derived products, including dried and canned fruits, beverages, jams, and jellies. Reporting precise type and/or quantity of grape and berries in FFQ or diaries can obviously be affected by errors. Recently, biomarkers of food intake (BFIs) rose as a promising tool to provide accurate information indicating consumption of certain food items. Protocols for performing systematic reviews in this field, as well as for assessing the validity of candidate BFIs have been developed within the Food Biomarker Alliance (FoodBAll) Project. This paper aims to evaluate the putative BIFs for blueberries, strawberries, raspberries, blackberries, cranberries, blackcurrant, and grapes. Candidate BFIs for grapes were resveratrol metabolites and tartaric acid. The metabolites considered as putative BFI for berries consumption were mostly anthocyanins derivatives together with several metabolites of ellagitannins and some aroma compounds. However, identification of BFIs for single berry types encountered more difficulties. In the absence of highly specific metabolites reported to date, we suggested some multi-metabolite panels that may be further investigated as putative biomarkers for some berry fruits.

【 授权许可】

CC BY