Tolerância à aplicação de megadoses de vitamina A associada à vacinação em crianças no Nordeste do Brasil

Cadernos de Saúde Pública

Ana Marlúcia Oliveira Assis²  Leonor Maria Pacheco Santos²  Matildes Da Silva Prado²  Maísa Cruz Martins¹  Maurício Lima Barreto¹ 

[1] ,Universidade Federal da Bahia Escola de Nutrição Salvador BA ,Brasil

关键词: Vitamin A;    Supplementary Feeding;    Immunization Program;    Vitamina A;    Suplementação Alimentar;    Programas de Vacinação;   

DOI  :  10.1590/S0102-311X2000000100006

来源: SciELO

【 摘 要 】

A follow-up study was carried out in two localities in the semi-arid region of the State of Bahia, Northeast Brazil, with the aim of identifying the occurrence and nature of possible acute side effects subsequent to vitamin A megadose supplement given together with mass immunization in children 6-59 months old. The sample consisted of 852 children, 416 from the county of Teofilandia who received vitamin A together with vaccines and 436 from Santa Barbara, who received only vaccine. In the 24 hours before immunization, children from both groups had similar incidences of diarrhea, fever, and vomiting. Anorexia was more prevalent in Teofilandia and remained so throughout the study period. The results suggest that acute side effects like diarrhea, vomiting, fever, or anorexia were not associated with the vitamin A dosage given with mass OPV, DPT, and measles immunization.

【 授权许可】

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