Erythropoietin resistance in end-stage renal disease patient with gastric antral vascular ectasia

Jornal Brasileiro de Nefrologia

Desiree Ji Re Lee¹  Juliana Fragata¹  José Osmar Medina Pestana¹  Sergio Draibe¹  Maria Eugênia Canziani¹  Miguel Cendoroglo¹  Miguel Ângelo De Góes Jr.¹ 

关键词: anemia;    chronic;    erythropoietin;    gastric antral vascular ectasia;    kidney failure;    anemia refratária;    ectasia vascular gástrica antral;    eritropoetina;    insuficiência renal crônica;   

DOI  :  10.5935/0101-2800.20150042

来源: SciELO

【 摘 要 】

AbstractWe observed a case of recombinant human erythropoietin resistance caused by Gastric Antral Vascular Ectasia in a 40-year-old female with ESRD on hemodialysis. Some associated factors such as autoimmune disease, hemolysis, heart and liver disease were discarded on physical examination and complementary tests. The diagnosis is based on the clinical history and endoscopic appearance of watermelon stomach. The histologic findings are fibromuscular proliferation and capillary ectasia with microvascular thrombosis of the lamina propria. However, these histologic findings are not necessary to confirm the diagnosis. Gastric Antral Vascular Ectasia is a serious condition and should be considered in ESRD patients on hemodialysis with anemia and resistance to recombinant human erythropoietin because GAVE is potentially curable with specific endoscopic treatment method or through surgical procedure.

【 授权许可】

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