Pesquisa Veterinária Brasileira | |
Transitional cell carcinoma of urinary bladder with metastasis in lumbar vertebrae and spinal cord compression in an ocelot(Leopardus pardalis) | |
Karen Y.r. Nakagaki1  Pâmela A. Lima1  Kiyoko U. Utiumi1  Marco A.m. Pires1  Rosana Zanatta1  Fabiana M. Boabaid1  Edson M. Colodel1  Djeison L. Raymundo1  | |
关键词: Transitional cell carcinoma; urinary bladder; ocelot; Leopardus pardalis; epithelialneoplasia; urinary system; immunohistochemistry; cytokeratin; wild feline.; Carcinoma de células de transição; bexiga urinária; jaguatirica; Leopardus pardalis; neoplasia epitelial; sistema urinário; imuno-histoquímica; citoqueratina; felino selvagem.; | |
DOI : 10.1590/S0100-736X2015000100015 | |
来源: SciELO | |
【 摘 要 】
This paper reports a case of nonpapillary and infiltrative transitional cell carcinoma (TCC) of the urinary bladder with metastasis of lumbar vertebrae and spinal cord compression in an adult female ocelot (Leopardus pardalis), from the Mato Grosso state, Brazil. The ocelot had pelvic limb paralysis and skin ulcers in the posterior region of the body and was submitted to euthanasia procedure. At necropsy was observed a multilobulated and irregular shaped, yellowish to white nodule in the urinary bladder. The nodule had a soft consistency and arised from the mucosa of the urinary bladder extending throughout the muscular layers and the serosa. Nodules of similar appearance infiltrating the vertebral column the at L6 and L7 vertebrae with corresponding spinal canal invasion were also observed. The histological evaluation showed epithelial neoplastic proliferation in the urinary bladder with characteristics of nonpapillary and infiltrative TCC, with positive immunohistochemical staining for pancytokeratin, and strong immunostaining for cytokeratin of low molecular weight, and weak or absent labeling for high molecular weight cytokeratin. This is the first report of TCC of urinary bladder in ocelot in Brazil.
【 授权许可】
CC BY-NC
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