Insights on bovine genetic engineering and cloning

Pesquisa Veterinária Brasileira

Fabiana F. Bressan¹  Juliano R. Sangalli¹  Laís V.f. Pessôa¹  Pedro R.l. Pires¹  Flávio V. Meirelles¹ 

[1] ,Universidade de São Paulo Faculdade de Zootecnia e Engenharia de Alimentos Departamento de Medicina VeterináriaPirassununga SP ,Brazil

关键词: Induced pluripotency;    transgenic technology;    somatic cell nuclear transfer;    cattle;    Pluripotência induzida;    tecnologia transgênica;    transferência nuclear de célula somática;    bovino;   

DOI  :  10.1590/S0100-736X2013001300018

来源: SciELO

【 摘 要 】

Transgenic technology has become an essential tool for the development of animal biotechnologies, and animal cloning through somatic cell nuclear transfer (SCNT) enabled the generation of genetically modified animals utilizing previously modified and selected cell lineages as nuclei donors, assuring therefore the generation of homogeneous herds expressing the desired modification. The present study aimed to discuss the use of SCNT as an important methodology for the production of transgenic herds, and also some recent insights on genetic modification of nuclei donors and possible effects of gene induction of pluripotency on SCNT.

【 授权许可】

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