Bovine herpesvirus type 5 (BHV-5) in a calf with rabies

Pesquisa Veterinária Brasileira

Fernando R. Spilki¹  Ana C. Franco¹  Marjorie B. Teixeira¹  Paulo A. Esteves¹  Rejane Schaefer¹  Eduardo Schmidt²  Ricardo A. Lemos¹  Paulo M. Roehe² 

[1] ,Universidade Federal do Rio Grande do Sul Departamento de Microbiologia Laboratório de VirologiaPorto Alegre RS ,Brasil

关键词: Bovine herpesvirus type 5;    BHV-5;    rabies;    Herpesvírus bovino tipo 5;    BHV-5;    raiva;   

DOI  :  10.1590/S0100-736X2003000100001

来源: SciELO

【 摘 要 】

The brain of an one year old male calf which died with signs of neurological disease was submitted to the laboratory for rabies diagnosis. Microscopical findings included moderate mielitis, mild meningoencephalitis with perivascular cell cuffing and Negri inclusion bodies in Purkinje cells of the cerebellum. Rabies virus infection was further confirmed by the direct fluorescent antibody test as well as by mouse inoculation. In addition, a herpesvirus was isolated from brain tissues. The isolate was antigenic and genetically characterized as bovine herpesvirus type 5 (BHV-5). It was not possible to determine whether BHV-5 played an active role in the outcome of the infection, since, the virus might have been present in a latent form in neural tissues. This is the first report of a mixed rabies/ BHV-5 infection in calves.

【 授权许可】

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