Revista do Colégio Brasileiro de Cirurgiões | |
Natural history of extensive diaphragmatic injury on the right side: experimental study in rats | |
Jorge Henrique Rivaben1  Roberto Saad Junior1  Vicente Dorgan Neto1  Marcio Botter1  Roberto Gonçalves1  | |
关键词: Diaphragm; Wound Healing; Diaphragm/injuries; Animal Experimentation; Diafragma; Cicatrização de Feridas; Diafragma/lesões; Experimentação Animal; | |
DOI : 10.1590/0100-69912014004008 | |
来源: SciELO | |
【 摘 要 】
OBJECTIVE: To evaluate the natural healing of the rat diaphragm that suffered an extensive right penetrating injury.METHODS: Animals were submitted to an extensive penetrating injury in right diaphragm. The sample consisted of 40 animals. The variables studied were initial weight, weight 21 days after surgery; healing of the diaphragm, non-healing of the diaphragm, and herniated abdominal contents into the chest.RESULTS: Ten animals were used as controls for weight and 30 animals were operated. Two animals died during the experiment, so 28 animals formed the operated group; healing of the diaphragm occurred in 15 animals (54%), 11 other animals showed diaphragmatic hernia (39%) and in two we observed only diaphragmatic injury without hernia (7%). Among the herniated organs, the liver was found in 100% of animals, followed by the omentum in 77%, small bowel in 62%, colon in 46%, stomach in 31% and spleen in 15%. The control group and the diaphragmatic healing subgroup showed increased weight since the beginning of the study and the 21 days after surgery (p <0.001). The unhealed group showed no change in weight (p = 0.228).CONCLUSION: there is a predominance of spontaneous healing in the right diaphragm; animals in which there was no healing of the diaphragm did not gain weight, and the liver was the organ present in 100% the diaphragmatic surface in all rats with healed diaphragm or not.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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