Comportamento eletroquímico e avaliação da difusão in vitro do α-tocoferol associado à iontoforese

Química Nova

Elisa Paludo²  Laís Bresciani¹  Maurício Hilgemann¹  João Alberto Tassinary²  Simone Stülp¹ 

[1] ,Centro Universitário UNIVATES Centro de Ciências Biológicas e da Saúde Lajeado RS ,Brasil

关键词: iontophoresis;    α-tocopherol;    electrochemical analysis;   

DOI  :  10.5935/0100-4042.20140232

来源: SciELO

【 摘 要 】

Iontophoresis is a method of administering substances through the skin, which uses electrical current or potential to promote transdermal delivery. We focused on α-tocopherol (vitamin E), a natural antioxidant able to reduce or block the oxidation reactions induced by free radicals in biological membranes. The aim of this study was to perform electrochemical evaluation and analysis of vertical diffusion of gel + α-tocopherol undergoing iontophoresis. The results showed a reduction in peak current at 0.78 V of α-tocopherol molecules when subjected to iontophoresis, increasing the diffusion and degradation of the system.

【 授权许可】

CC BY-NC   
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