Síntese da Epoxone a partir de D-frutose: um experimento didático em laboratório de Química Orgânica com foco nos princípios da Química Verde

Química Nova

Tula Beck Bisol¹  Marcelo Volpatto Marques¹  Thaís Andreia Rossa¹  Maria Da Graça Nascimento¹  Marcus Mandolesi Sá¹ 

[1] ,Universidade Federal de Santa Catarina Departamento de Química Florianópolis SC ,Brasil

关键词: epoxone;    D-fructose;    green chemistry;   

DOI  :  10.1590/S0100-40422012000600035

来源: SciELO

【 摘 要 】

In recent years, the introduction of the Green Chemistry concepts in undergraduate chemistry classes has been intensively pursued. In this regard, the two-step preparation of Epoxone (an organocatalyst developed by Shi & col.) from commercial D-fructose, through ketalization of vicinal diols followed by oxidation of a sterically congested secondary alcohol, involves important topics in Organic Chemistry and employs inexpensive and nontoxic reagents. The reactions are easy to perform and the products from both steps are readily obtained as crystalline solids after simple procedures, thus facilitating their chemical characterization.

【 授权许可】

CC BY-NC   
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